第5課:MTF 女性化荷爾蒙療法入門
💊Part 1:藥物解密(抗雄激素 & 雌激素)
▫️ 抗雄激素藥物:
• 任務:截停睾丸素生產 + 堵塞接收器🚫
• 效果:鬍鬚生長慢鏡頭/肌肉流失mode/性慾休眠
• 常用藥物:Spironolactone(利尿劑變身)、Cyproterone(較爲常用)
▫️ 雌激素:
• 任務:重新粉刷身體🎨(脂肪搬遷/皮膚拋光/胸部建模)
• 副業:順手壓制睾丸素(一箭雙鵰🏹)
• 派送方式:
吞藥丸(經肝臟高危⚠️)
皮膚吸收gel(阿婆貼膏藥式)
打針見效快(香港沒有)
⚖️ 一般MTF藥物組合:
「抗雄 + 雌激素」雙劍合璧!但劑量比例要請教醫生——
• 後生仔:可能只需少量抗雄
• 中年轉性:要加強阻截睾丸素
• 雌激素不是越多越好!
🌷Part 2:變身清單(預期效果)
▫️ 永久(不可逆)反應:
• 胸部發育(大小睇基因彩票🎰)
• 蛋蛋縮水變軟(似漏氣波仔⚽)
• 生育能力bye bye(精子產量急跌📉)
▫️ 可逆反應:
• 肌肉量減磅(變「棉花手」💪🏻→🤚🏻)
• 脂肪搬屋到patpat(自帶天然坐墊🍑)
• 皮膚滑過原本(暗瘡say goodbye✨)
• 體毛生長慢半拍(剃鬚費慳唔少✂️)
⚠️ 走盏位:
• 聲線唔會自動變少女(要夾聲練習🎤)
• 喉核照舊凸出(可考慮手術削平🔪)
• 骨架係定海神針(盆骨唔會自然變闊🚫)
🩺Part 3:風險雷達圖(輔導員急救包)
▫️ 身體紅燈區:
• 血栓危機(長途飛機要踢腿🛫)
• 心血管壓力(食煙人士高危🚭)
• 血壓坐過山車(定期check住📊 )
• 肝功能打暗號(戒酒為上策🍺❌)
▫️ 生殖警報器:
• 生仔能力可能永久封印(雪精要趁早❄️)
• 避孕唔可以偷雞(照樣會搞出人命👶)
• 腦下垂體生腫瘤(定期MRI掃描🧲)
▫️ 情緒過山車:
• 初期可能狂嘔(似陀仔三個月🤮)
• 心情時晴時雨(要set情緒安全網🌦️)
• 乳房檢查唔偷懶(每年mammogram📅)
要根據醫生指示定期驗血檢查!
Reference:
Cunha, F.S., Klaver, M., Nota, N.M., T’Sjoen, G. and den Heijer, M., 2018. Prolactinemia in transgender individuals during hormone therapy: A systematic review. The Journal of Clinical Endocrinology & Metabolism, 103(11), pp.3927–3934. [online] Available at: https://academic.oup.com/jcem/article/103/11/3927/4102170 [Accessed 6 March 2025].
Hembree, W.C., Cohen-Kettenis, P.T., Gooren, L., Hannema, S.E., Meyer, W.J., Murad, M.H., Rosenthal, S.M., Safer, J.D., Tangpricha, V. and T’Sjoen, G.G., 2017. Endocrine treatment of gender-dysphoric/gender-incongruent persons: An Endocrine Society clinical practice guideline. The Journal of Clinical Endocrinology & Metabolism, 102(11), pp.3869–3903. [online] Available at: https://academic.oup.com/jcem/article/102/11/3869/4130391 [Accessed 6 March 2025].
Planned Parenthood, 2022. Hormone therapy for transgender adults. [online] Available at: https://www.plannedparenthood.org/learn/gender-identity/transgender/hormone-therapy-for-transgender-adults [Accessed 6 March 2025].
UCSF Transgender Care, n.d. Gender-affirming hormones. [online] Available at: https://transcare.ucsf.edu/transitioning/gender-affirming-hormones [Accessed 6 March 2025].
World Professional Association for Transgender Health (WPATH), 2022. Standards of Care for the Health of Transgender and Gender Diverse People, Version 8. [online] Available at: https://www.wpath.org/publications/soc [Accessed 6 March 2025].